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KMID : 1171820050200020033
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Journal of Environmental and Sanitary Engineering
2005 Volume.20 No. 2 p.33 ~ p.38
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Sustained Release Properties of Vitamin C in Chitosan Molecular network
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Han Sang-Mun
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Abstract
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Chitosan is a dietary fiber because of a linear polysaccharide composed of β-(1→4)-linked 2-amino-2-deoxy-D-glucopyranose. In this study, control release system of vitamin C has been estimated in chitosan molecular network as a vitamin C carrier of controlled release. The amount of released vitamin C were decreased in higher amount of chitosan concentration. Especially, vitamin C were slowly released from chitosan solution in dialysis membrane when compared with vitamin C solution alone in dialysis membrane. These result assumed that chitosan driving force is dependent on chitosan molecular weight and cationic property of amino group with anionic property of vitamin C.
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KEYWORD
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chitosan, Vitamin C, drug control release device, chitosan molecular network
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